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Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury 被引量:16

Prevention and management of non-steroidal anti-inflammatory drugs-induced small intestinal injury
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摘要 Non-steroidal anti-inflammatory drug (NSAID)-induced small bowel injury is a topic that deserves attention since the advent of capsule endoscopy and balloon enteroscopy. NSAID enteropathy is common and is mostly asymptomatic. However, massive bleeding, stricture, or perforation may occur. The pathogenesis of small intestine injury by NSAIDs is complex and different from that of the upper gastrointestinal tract. No drug has yet been developed that can completely prevent or treat NSAID enteropathy. Therefore, a long-term randomized study in chronic NSAID users is needed. Non-steroidal anti-inflammatory drug Nindu cedsmall bowel injury is a topi that deserves attentionsin e the advent of apsule endos opy and balloon enteros opy. N enteropathy is ommon and is mostly asymptomati . However,massive bleeding,stri ture,or perforation may o ur. The pathogenesis of small intestine injury by N s is omplex and different from that of the upper gastrointestinal tra t. No drughas yet been developed that an ompletely preventor treat N enteropathy. There fore,a long-termr and omized study in hroni N users is needed.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第42期4647-4653,共7页 世界胃肠病学杂志(英文版)
关键词 Non-steroidal anti-inflammatory drugs Small intestinal injury PREVENTION TREATMENT 非甾体抗炎药 消炎药 小肠 损伤 预防 管理 发病机制 双气囊
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