摘要
目的:评价奥拉西坦改善脑梗死患者认知功能的临床疗效。方法:入选脑梗塞患者96例,随机分为奥拉西坦组(采用奥拉西坦为主的治疗方案)和常规治疗对照组(采用常规治疗),各48例。运用简易精神状态量表(MMSE)和巴氏指数(BI)测定治疗前后两组患者的分值,并进行比较分析。结果:治疗一个月后,两组MMSE、BI分值均较治疗前有明显提高(P<0.05~0.01),且奥拉西坦组MMSE[(21.52±7.83)分比(16.75±6.27)分]、BI[(88.17±11.39)分比(79.97±13.36)分]分值明显高于常规治疗对照组(P<0.05)。结论:奥拉西坦可显著改善脑梗死患者的认知功能。
Objective: To evaluate clinical effects of oxiracetam on improvement of cognition in patients with cerebral infarction. Methods: A total of 96 patients with cerebral infarction were randomly and equally divided into oxiracetam group (received treatment with oxiracetam based on routine treatment) and routine treatment control group (re- ceived routine treatment). Mini-mental state examination (MMSE) and Barthel index (BI) were used to measure cognition condition of the two groups before and after treatment, and the results were compared and analyzed. Resalts: After one month treatment, scores of MMSE and BI significantly increased in the two groups compared with before treatment (P〈0.05-〈0.01), and scores of MMSE and BI in oxiracetam group were significantly higher than those of routine treatment control group [MMSE (21.52±7.83) scores vs. (16.75±6.27) scores, BI (88.17± 11.39) scores vs. (79.97± 13.36) scores, P〈0.05 both]. Conclusion: Oxiracetam can significantly improve cognition of patients with cerebral infarction.
出处
《心血管康复医学杂志》
CAS
2011年第6期556-558,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
奥拉西坦
脑梗塞
认知
Oxiracetam
Brain infarction
Cognition