老年下呼吸道感染患者中的血清降钙素原与超敏C-反应蛋白的相关性分析

The correlation analysis of serum procalcitonin and high-sensitive C-reactive protein in patients with lower respiratory tract infections in the elderly

目的探讨血清降钙素原(PCT)与超敏C-反应蛋白(hs-CRP)检测结果在老年下呼吸道感染中的相关性。方法 80例老年下呼吸道感染患者入院后24h内检测PCT、hs-CRP,并进行相关分析。结果 hs-CRP与PCT呈正相关(r=0.342,P<0.01),PCT阳性率为85.0%,明显高于hs-CRP(17.5%),PCT灵敏度分别为85.0%、82.5%;PCT、hs-CRP的特异度分别为90.0%、48.3%;两者相比较差异有统计学意义(χ2=47.032,P<0.01)。结论 PCT与hs-CRP检测结果呈正相关,PCT测定诊断老年下呼吸道感染的特异度高于hs-CRP。

Objective To investigate the relevance of the serum procalcitonin （PCT） and the high sensitive Creactive protein （hs-CRP） in patients with lower respiratory tract infections （LRTI） in the elderly. Methods 80 patients with LRTI in the elderly were collected and observed. Serum procaltionin and hs CRP were tested within the first 24 hours. Results Significant positive correlation between PCT and hs-CRP （r=0. 342,P〈0.01） was found, and the positive rate of PCT was 85.0% ,which was significantly higher than that of hs-CRP 17.5%. While the sen sitivity of PCT and hs CRP were 85.0% and 82.5% ; The specificity of PCT and hs-CRP were 90.0% and 48.3%, while statistically significant difference were found between them （x2=47. 032,P〈0.01）. Conclusion Significantly positive correlation was found between PCT and hs-CRP, in diagnosis,the specificity of PCT determination is higher than that of hs-CRP measurement.