肾移植受者移植肾带功能死亡与失功能死亡原因比较

Comparision of death causes between kidney transplant recipients died with a functioning graft and those died after graft loss

目的分析肾移植受者移植肾带功能死亡与失功能死亡原因。方法回顾分析我院2001年至2010年期间死亡的207例肾移植受者资料。将其分为移植肾带功能死亡组（102例）和失功能死亡组（105例），对两组死亡原因进行比较分析。结果所有受者的死亡原因依次为感染（31．9％）、心血管疾病（21．3％）、肝功能衰竭（15．9％）、其他死亡原因（12．1％）、脑血管疾病（7．7％）、消化道出血（6．3％）和肿瘤（4．8％）；失功能死亡组中因心血管疾病死亡的患者例数明显多于带功能死亡组（P=0．02），其他死亡原因两组差异无统计学意义。结论移植肾失功能显著增加肾移植受者因心血管疾病死亡的风险。

Objective To analyze the difference of the death causes between kidney transplant recipients died with functioning graft and those died after graft loss. Methods The clinical data of 207 cases of cadaveric kidney transplant recipients died between 2001 and 2010 were analyzed retrospectively. The data were divided into death with functioning graft group （n = 102） and death after graft loss group （n = 105）. Then the death causes of the two groups were compared and analyzed. Results Generally the death causes were infection （ 31.9 % ）, cardiovascular disease （21.3 % ）, hepatic failure （ 15.94% ）, others （ 12.1% ） ,stroke （7.7%） ,gastric ulcer （6.3%） and malignant disease （4.8%） in turn. Death after graft loss group had much more patients died from cardiovascular disease than the other group（ P = 0.02） ; There was no significant difference in the incidence of other causes of death between the two groups. Conclusion Graft loss increases the incidence of cardiovascular death among kidney transplant recipients.