溶血-肝酶升高-血小板减少综合征23例临床分析

Clinic analysis of 23 cases with HELLP syndrome

目的探讨溶血-肝酶升高-血小板减少（HELLP）综合征的诊断和治疗方法。方法对我院自2005年2月-2010年11月收治的23例溶血-肝酶升高-血小板减少综合征患者的临床资料进行回顾性分析。结果23例溶血-肝酶升高-血小板减少综合征中急进型11例，非急进型12例。急进型溶血-肝酶升高-血小板减少组AST、ALT、LDH值及孕产妇并发症发生率和死亡率均明显高于非急进型溶血-用：酶升高-血小板减少组，而血小板计数明显低于非急进型溶血．肝酶升高一血小板减少组（P〈0．05）。结论溶血-肝酶升高-血小板减少综合征是严重威胁母婴安全的并发症，早期诊断，及时终止妊娠可大大降低母婴死亡率。

Objective To explore the clinical experiences in the diagnosis and treatments of HELLP syndrome. Methods The clinic data of 23 patients with HELLP syndrome admitted in our hospitaX from February 2005 to November 2010 were analyzed retrospectively. Results All HELLP syndrome patients were divided into two groups, radical-type（ 11 cases） and non-radical-type（ 12 cases）. The value of AST and LDH as well as complication incidence of patients and maternal mortality in radical-type HELLP syndrome were significantly higher than that in non-radical-type HELLP syndrome, while the value of PLT in radical-type HELLP syndrome were significantly lower than that in non-radical-type HELLP syndreme（ P 〈 0.05 ）. Conclusion HELLP syndrome is a kind of serious complication threatened to the safety of both mother and infant. Early diagnosis and pregnancy termination in time can greatly decrease the mortality of both mother and infant.