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57例耐碳青霉烯类药物鲍曼不动杆菌肺部感染患者的临床分析 被引量:1

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摘要 目的了解耐碳青霉烯类药物鲍曼不动杆菌肺部感染患者的I临床特点。方法分析57例碳青霉烯类药物鲍曼不动杆菌肺部感染患者的临床症状、体征、肺部影像学改变、细菌耐药现状及治疗转归等。结果57例患者临床表现以发热、咳嗽、咳痰多见,多伴有血象升高、影像学改变,超过50%的患者有多种抗生素联合使用、病程中使用碳青霉烯类药物抗感染、机械通气病史。23例(40.4%)患者死亡。痰培养提示此菌仅对多粘菌素B、米诺环素、头孢哌酮\舒巴坦耐药率在50%以F。结论临床上应重视耐碳青霉烯类鲍曼不动杆菌所引起的肺部感染,其死亡率较高,抗生素的使用可能会诱导耐药产生,耐碳青霉烯类鲍曼不动杆菌对大部分临床常用抗生素耐药,经验性用药可考虑头孢哌酮\舒巴坦、多粘菌素B和米诺环素。
出处 《临床内科杂志》 CAS 2011年第11期776-777,共2页 Journal of Clinical Internal Medicine
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