庆大霉素、地塞米松、糜蛋白酶混合注射液根管内封药治疗慢性根尖周炎58例疗效观察

CLINICAL OBSERVATION OF SEALING DRUG MIXED GENTAMICIN,DEXAMETHASONE AND CHYMOTRYPSIN IN ROOT CANAL OF CHRONIC PERIAPICAL

目的观察庆大霉素、地塞米松、糜蛋白酶注射液根管内封药治疗慢性根尖周炎的临床疗效。方法选择116例慢性根尖周炎的患牙,随机分成二组,根管治疗过程中分别采用庆大霉素、地塞米松、糜蛋白酶混合注射液和传统的根管内消毒药物樟脑对氯酚(CMCP)根管内封药,对疗效结果进行比较。结果庆大霉素、地塞米松、糜蛋白酶混合注射液根管内封药组总有效率(93.10%)优于对照组CMCP根管内封药(68.97%),二组疗效比较差异有统计学意义(P<0.05)。结论庆大霉素、地塞米松、糜蛋白酶注射液根管内封药对于病程长,长期渗出、疼痛、根尖炎症较大的病例较CMCP能更有效的控制症状。

Objective To observe the clinical efficacy of gentamicin,dexamethasone,chymotrypsin mixture injection in root canal of chronic periapical which sealed in root canal treatment.Methods 116 cases of teeth with chronic periapical were chose which divided into two groups.The treated group was seal mixture injection of gentamicin,dexamethasone,chymotrypsin and the control group was given camphor-chlorophenol（CMCP） of conventional root canal disinfectants in root canal.The efficacy was compared.Results The total efficiency（93.10%） of treated group was higher than the control group CMCP sealing durg（68.97%）.The efficiency of two groups was statistically significant（P0.05）.Conclusion The mixed injection drug of sealing gentamicin,dexamethasone,chymotrypsin in root canal can effectively control the symptoms of cases with longer duration,long-term leakage,pain than the group of sealing CMCP.