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细胞凋亡调节基因GW112及GRIM-19的研究进展 被引量：1

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摘要 OLFM4GW112/hGC-1（olfactomedin 4,又名GW112,hGC-1）和GRIM-19（Genes assoeiated with retin-oid-IFN-induced mortality-19）是近年来发现的基因,它们通过多种机制来参与细胞凋亡。GW112是抗凋亡基因,促进肿瘤的生长,其在很多人类肿瘤中,特别是消化系统肿瘤中高表达。同时GW112与GRIM-19相互关联,而GRIM-19的正常表达可以维持细胞正常的生活周期,使细胞从衰老进入凋亡。近年来,GW112与GRIM-19受到人们的广泛关注,本文主要综述了二者与细胞凋亡的关系。
作者 吴清 陈海军 钱宏亮
机构地区 南京中医药大学附属昆山医院
出处 《中国煤炭工业医学杂志》 2011年第11期1726-1727,共2页 Chinese Journal of Coal Industry Medicine
关键词 GW112 GRIM-19 细胞凋亡
分类号 R573 [医药卫生—消化系统]
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参考文献14

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共引文献64

同被引文献12

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中国煤炭工业医学杂志
2011年 第11期

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