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心肌再生的研究进展 被引量:4

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摘要 对于有心脏病的患者来说,心肌再生修复可能是最有前景的治疗措施。然而,成人心肌细胞更新的速度非常缓慢,这使得损失的心肌很难恢复。自然界中,成年斑马鱼和蝾螈的心肌能够完全再生,一般认为是由成熟的心肌细胞去分化增殖形成;刚出生的小鼠心肌也具有完全再生的能力,新的心肌细胞可能来源于心肌干细胞或者成熟的心肌细胞去分化。近年来,将诱导多能干细胞再分化,或将成纤维细胞转分化或"重编程"成心肌细胞已成为探索心肌细胞再生的重要途径。随着对心肌再生机制研究的的不断深入,人们最终将实现心肌再生的临床应用。
出处 《中国循环杂志》 CSCD 北大核心 2011年第6期480-482,共3页 Chinese Circulation Journal
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参考文献20

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共引文献7

同被引文献69

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