中西医结合治疗活动期溃疡性结肠炎的疗效

Observation on the efficacy of combined treatment of Chinese and Western medicine in active ulcerative colitis

目的:探讨中西医结合[千喜片+水杨酸柳氮磺胺吡啶片(SASP)+泼尼松]治疗活动期溃疡性结肠炎(UC)的疗效。方法:将70例活动期UC患者按随机数字表法平均分为治疗组(予以千喜片+SASP+泼尼松治疗)和对照组(予以SASP+泼尼松治疗),治疗1个疗程后,观察两组临床疗效和不良反应。结果:治疗组显效率明显高于对照组(P<0.05),有统计学意义;治疗组总有效率与对照组无统计学意义(P>0.05),治疗组不良反应发生率与对照组比无统计学意义(P>0.05)。结论:SASP加糖皮质激素基础上加用中成药千喜片治疗活动期UC的显效率明显优于使用SASP加糖皮质激素的疗效,值得临床推广。

Objective：To observe the effect of integrated Chinese-western therapy（Qiangxipian tablet ＋ salicylic acid tablets sulfasalazine（SASP） ＋ prednisone） for ulcerative colitis（UC） in active phase.Methods：Seventy patients with active UC patients were evenly allocated to treatment group（Qiangxipian tablet ＋ salicylic acid tablets sulfasalazine（SASP） ＋ prednisone） and control group（salicylic acid sulfasalazine SASP tablets（SASP） ＋ prednisone） at random.The two groups were observed for the clinical efficacy and adverse reactions after one course of therapy.Results：The curative rate was significantly higher in the treatment group than that of the controls（P0.05）,and yet,the two groups showed no significant difference regarding the total effective rate and adverse effects（P0.05）.Conclusion：Qiangxipian tablet ＋ SASP ＋ prednisone is superior to SASP ＋ prednisone therapy for ulcerative colitis in active phase and worthy of wider clinical use.