声辐射力脉冲成像技术对脑梗死患者颈动脉粥样软斑块质地的检测

Detection of the texture of carotid soft plaques in patients with cerebral infarction using acoustic radiation forceimaging

目的 应用声辐射力脉冲成像（acoustic radiation force imaging,ARFI）技术定量评价脑梗死和非脑梗死患者颈动脉粥样软斑块的质地.方法 71例颈动脉粥样软斑块患者分为脑梗死组（31例）与非脑梗死组（40例）,分别对各个斑块行ARFI检查,记录各斑块的剪切波传播速度（shear wave velocities,SWV）.对两组斑块的SWV进行比较.结果 脑梗死组软斑的SWV比非脑梗死组慢,差异有统计学意义（P=0.027）.绘制ROC曲线,以斑块组织SWV=1.262 m/s为截点预测脑梗死的敏感性和特异性分别为67.7％和70.0％.结论 ARFI技术可对颈动脉粥样软斑块质地进行定量检测,以预测脑梗死的发生.

Objective To quantitatively assess the texture of carotid soft plaques in patients with or without cerebral infarction using acoustic radiation force imaging（ARFI）.Methods A total of 71 patients with carotid soft plaques were divided into two groups：group A including 31 patients with cerebral infarction and group B including 40 patients without cerebral infarction.ARFI was used to measure the shear wave velocities（SWV） of each soft plaque of the two groups.The results of two groups were compared.Receiver operating characteristic（ROC） curve was drawn to assess the diagnostic accuracy.Results The value of SWV between two groups were significantly different （ P =0.027）.The sensitivity and specificity of SWV （AUC =0.667,cut-off value =1.262 m/s） in predicting cerebral infarction was 67.7% and 70.0% respectively.Conclusions The texture of carotid soft plaques can be evaluated quantitatively using ARFI which was strongly related with cerebral infarction.