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角膜新生血管抑制药物的研究进展 被引量:1

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摘要 角膜在病理因素的作用下产生新生血管,角膜新生血管不但严重影响视力,而且容易导致角膜移植手术的失败。近年来,随着对眼部新生血管和肿瘤的深入研究,在血管生成的发病机制和新生血管抑制剂方面的研究已取得了迅猛发展,但角膜新生血管的治疗依然是目前最为棘手的医学难题之一。此文综述了近年来角膜新生血管的药物治疗进展。
出处 《中国实用眼科杂志》 CSCD 北大核心 2011年第12期1215-1218,共4页 Chinese Journal of Practical Ophthalmology
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参考文献23

  • 1杨培增主编.眼科学基础与临床.北京:人民卫生出版社,2005:55-61.
  • 2Duenas Z,Torner L,Corbach AM,et al.Inhibition of rat corneal angiogenesis by 16kDa prolactin and by endogenous prolact in like molecules[J].Invest Ophthalmol Vis Sci,1999,40:2498-2505.
  • 3袁中芳,魏增涛,王晓燕.重组内皮抑素抑制兔角膜新生血管的实验研究[J].山东大学耳鼻喉眼学报,2006,20(6):552-554. 被引量:5
  • 4赵晶,彭清,高燕,王小刚,高昭,王平.贝伐单抗抑制兔角膜碱烧伤新生血管的实验研究[J].中国医疗前沿,2010,5(13):17-18. 被引量:2
  • 5Book F,Konig Y,Kruse F,et al.Bevacizumab (Avastin)eye drops inhibit corneal neovascularization[J].Graefes Arch Clin Exp Ophthalmol DO110,1007/s00417-007-0684-4.
  • 6Rosenfeld PJ.Schwaz SD.Blumenkranz MS,et al.Maximum tolerated dose of a humanized antivascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration[J].Ophthalmology,2005,112(6):1048-1053.
  • 7Shukla D,Namperumalsamy P,Goldbaum M,et al.Pegaptanib sodium for ocular vascular disease[J].nelian Ophthalmol,2007,55 (6):427-430.
  • 8Murata M,Shimizu S,Horiuchi S,et al.Inhibitory elect of triamcinolone acetonide on corneal neovascularization[J].Graefe's Arch Clin Exp Opbthalmol,2006,244(2):205-209.
  • 9Jain AK,Bansal R,Felcida V,et al.Evaluation of impression smear in the diagnosis of fungal keratitis[J].Indian J Ophthalmol,2007,55(1):33-36.
  • 10Takezawa Y,Shiraishi A,Noda E,et al.Effectiveness of in vivo confocal micraoscopy in detecting filamentous fungi during clinicalcourse of fungal keratitis[J].Cornea,2010,29(12):1346-1352.

二级参考文献78

  • 1邓文香.角膜碱烧伤早期应用皮质类固醇疗效观察[J].眼外伤职业眼病杂志,2004,26(6):385-386. 被引量:7
  • 2董莹,黄一飞,王丽强,陈兵.雷帕霉素抑制大鼠角膜移植免疫排斥反应的实验研究[J].中华眼科杂志,2005,41(10):930-935. 被引量:14
  • 3张坡,黄岚,朱光旭,崔斌,宋明宝,周音频,赵晓晖,尹阳光.雷帕霉素对内皮祖细胞增殖、黏附及迁移能力影响的实验研究[J].中华心血管病杂志,2006,34(11):1021-1025. 被引量:10
  • 4杨艳,张明昌,张波.血管内皮生长因子及其受体在大鼠碱烧伤后角膜新生血管中的表达[J].国际眼科杂志,2006,6(6):1320-1322. 被引量:15
  • 5Azar DT. Corneal angiogenic privilege: angiogenie and antiangiogenic factors in corneal avascularity, vaseulogenesis, and wound healing [ J ]. Trans Am Ophthalmol Soc ,2006,104: 264 -302.
  • 6Tong JP, Chan WM, Liu DT, et al. Aqueous humor levels of vascular endothelial growth factor and pigment epithelium-derived factor in polypoidal choroidal vasculopathy and choroidal neovascularization [ J ]. Am J Ophthalmol,2006,141 : 456 - 462.
  • 7Tammela T, Enholm B, Alitalo K, et al. The biology of vascular endothelial growth factors[ J]. Cardiovasc Res, 2005, 65:550-563.
  • 8Baldwin ME, Halford MM, Roufail S, et al. Vascular endothelial growth factor D is dispensable for development of the lymphaticsystem [ J J]. Mol Cell Biol,2005,25 : 2441 - 2449.
  • 9Cursiefen C,Chen L,Borges LP,et al. VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment [ J ]. J Clin Invest, 2004,113 ( 7 ) : 1040 - 1050.
  • 10Cursiefen C. Cao J, Dben L, et al. Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival [J ]. Invest Ophthalmol Vis Sci ,2004,45 ( 8 ) : 2666 - 2673.

共引文献22

同被引文献13

  • 1李昌吉,詹承烈,屈炳之,王秀兰,杨用祥,李洪洋,曾习明.眼刺激试验方法标准化的探讨——一种新眼液的兔眼刺激试验[J].现代预防医学,1991,18(4):193-195. 被引量:2
  • 2郭学良,林庚金,王杰军,高勇,钱立平,傅丽娜,许青.多西他赛调控LS174T细胞血管生成因子的作用[J].复旦学报(医学版),2003,30(3):200-203. 被引量:1
  • 3Vacra A, Rihalti D, lurlaro M, el al.Docetaxei versus Pat-litax-el for antiangiogenesis[J]. J Hemalolher Stem Cell Kes, 2002. 11(1 ): 103 -118.
  • 4Philipp W. Speicher L, Hunipel C. Expression of vascular en-dothelial growth factor and its receptors in inflamed and vascu-larized human corneas [J]. Invest Ophthalmol Vis Sci, 2000,41 (9): 2514-2522.
  • 5周金子,夏晓波.杨卓,等.兔角膜碱烧伤后VKGF的表达与新生血管的关系[J]. 国际服科杂志,2007,7(6):1543-46.
  • 6Edelman JL, Castro MK, Wen Y. Correlation of VEGK expres-sion in leukocytes with the growth and regression of blood ves-aeLs in the ral cornea [J]. Invest Ophthalmo] Vis Sci, 1999,40:1112-1123.
  • 7Kvanta A, Samian S, Fagerholm P, et al. Expression of ma-trix nietallon)leinase-2 (MMP-2) and vascular endothelialgrowtli factor ( VEGF') in inilammation—associated corneal neo-vascularization[J]. Exp Kye Kes, 2000, 70: 419-428.
  • 8Rihatti D. The crucial role of vascular permeability factor/vascu-lar endothelial growth factor in angiogenesis : a historical re-view [J]. British Journal of Haematology,2005,128(3): 303-9.
  • 9林芳,高晓唯,任兵,肖云,杨玉洁.Avastin对大鼠角膜新生血管的抑制及超微结构的影响[J].国际眼科杂志,2009,9(4):668-672. 被引量:7
  • 10常岩,蔡莉,王雨生,王海燕,李曼红.贝伐单抗眼液对兔眼角膜新生血管抑制作用的实验研究[J].眼科新进展,2010,30(7):605-611. 被引量:6

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