芪蓉润肠口服液配合腹部按摩治疗老年肺癌患者便秘的临床研究

Clinical Study of Qirong Runchang Oral Liquid Therapy with Abdominal Massage on Constipation in Elder Patients with Lung Cancer

目的探讨芪蓉润肠口服液配合腹部按摩治疗老年肺癌患者便秘的临床疗效。方法采用随机对照研究,将64例老年肺癌便秘患者随机分为两组:A组为治疗组,予芪蓉润肠口服液20ml/次,2/日,配合腹部按摩2/日;B组为对照组,予芪蓉润肠口服液20ml/次,2/日。记录两组病人治疗后达到起效和有效的时间及治疗前后排便频率、排便时间、大便性状及排便困难程度的评分情况。结果治疗组的显效率为71.9%,总有效率为93.8%;对照组的显效率为51.6%,总有效率为87.1%;两2组有效率比较差异有统计学意义(P<0.05);从起效和显效时间上比较,治疗组明显优于对照组(P<0.05);治疗后两组各症状指标均有显著改善,且治疗组治疗后在排便频率、时间及大便性状评分方面与对照组比较差异有统计学意义(P<0.05)。结论芪蓉润肠口服液配合腹部按摩,能更快更有效地增加排便频率,改善大便性状,减轻排便困难程度。

Objective To observe the effect of Qirong Runchang Oral Liquid Therapy with abdominal massage on constipation in elder patients with lung cancer. Methods 64 elder patients with lung cancer accompanied by constipation were randomized into 2 groups： therapy group （32 patients） was treated with Qirong Runchang Oral Liquid （20ml, bid） and abdominal massage （5-10min, bid）simultaneously; controlled group （32 patients） was treated with Qirong Runchang Oral Liquid alone（20ml, bid）. Symptoms including frequency, time, difficulty of defecation and quality of feces were recorded and accessed by score system. Results ①In therapy group, significant efficacy was 71.8% and the overall efficacy was 93.7% while in controlled group, significant efficacy was 51.6% and the overall efficacy was 87.1%; efficacy was significantly different in these two group （P〈0.05）. ②Less time was needed in therapy group to benefit from intervention （P〈0.05）. ③Score of symptoms in therapy group got more significantly improved compared with controlled group （P〈0.05）. Conclusion Qirong Runchang Oral Liquid therapy with Abdominal Massage could effectively improve constipation.