肿瘤细胞糖酵解途径的抗肿瘤研究

Anticancer based on glycolysis pathway in tumor cells

肿瘤细胞的葡萄糖代谢主要呈现出瓦博格效应（Warburg effect）。近年来，越来越多的实验证实基于肿瘤细胞有氧糖酵解途径的治疗可通过抑制多种分子、基因和信号途径限制能量供应，抑制肿瘤细胞增殖。这为肿瘤的靶向治疗提供了契机，具有巨大的潜在优势和广阔的临床应用前景。

Glucose metabolism of cancer ceils presents Warburg effect. In resent years, more and more experiments demonstrate that the therapeutics based on aerobic glycolysis pathway in cancer cells restrict energy and inhibit tumor proliferation through the inhibition of a Variety of moleculars, genes and signal pathways. These can provide an opportunity for targeted cancer therapies and possess enormous potential advantages and broad prospects in clinical application,