美国乳腺与肠道外科辅助治疗研究组结直肠癌临床试验研究进展

Advances on National Surgical Adjuvant Breast and Bowel Project colorectal cancer trials

美国乳腺与肠道外科辅助治疗研究组由美国国家癌症研究中心资助，主要进行大规模乳腺癌和结直肠癌临床试验。其临床试验为乳腺癌以及结直肠癌的治疗提供了重要的参考和指导价值。近5年来，NSABP结直肠癌临床试验就新的辅助化疗方案、靶向药物的作用以及直肠癌的新辅助治疗和辅助治疗的作用进行了深入的研究，取得了一些新的进展。

The National Surgical Adjuvant Breast and Bowel Project （NSABP） is a clinical trials cooperative group supported by the National Cancer Institute （NCI）. The NSABP has conducted clinical trials in breast and colorectal cancer for nearly 40 years, many of which have greatly improved the therapies in breast and colorectal cancers. There have been some new advances on new adjuvant chemotherapy regimens, targeted therapy, adjuanvt and neoadjuvant therapies for rectal cancer in recent 5 years.