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晚期胆道系统肿瘤的内科治疗 被引量:1

Medical therapy of advanced biliary tract cancer
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摘要 内科治疗是治疗晚期胆道系统肿瘤的重要手段。吉西他滨是最有效的药物之一,吉西他滨联合顺铂已成为标准方案。二线方案的相关研究甚少。靶向治疗有望成为新的标准,但需大型临床试验证实。 Medical therapy is the primary choice for patients with advanced biliary tract cancer. Gemeitabine has been proved to be one of the most effective drugs and a standard regimen has been made when combined with cisplatin. Studies of the second line therapy is few. Targeted therapy has a potential to create a new era in the future but needs to be validated in large clinical trials.
出处 《国际肿瘤学杂志》 CAS 2011年第12期933-936,共4页 Journal of International Oncology
关键词 胆道肿瘤 药物疗法 分子靶向治疗 Biliary tract neoplasms Drug therapy Molecular targeted therapy
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参考文献18

  • 1Thomas MB. Biological characteristics of cancers in the gallbladder and biliary tract and targeted therapy. Crit Rev Oncol Hematol, 2007, 61(1) :44-51.
  • 2Suzuki E, Furuse J, Ikeda M, et al. Treatment efficacy/safety and prognostic factors in patients with advanced biliary tract cancer receiving gemcitabine monotherapy: an analysis of 100 cases. Oncology, 2010, 79(1-2) :39-45.
  • 3Valle JW, Wasan H, Johnson P, et al. Gemcitabine alone or in combination with cisplatin in patients with advanced or metastatic cholan- giocarcinomas or other biliary tract tumours : a multicentre randomised phase II study--The UK ABC-01 Study. Br J Cancer, 2009, 101 (4) :621-627.
  • 4Valle J, Wasan H, Palmer DH, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med, 2010, 362 (14) :1273-1281.
  • 5Knox JJ, Hedley D, Oza A, et al. Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial. J Clin Oncol, 2005, 23 (10) :2332-2338.
  • 6Koeberle D, Saletti P, Borner M, et al. Patient-reported outcomes of patients with advanced biliary tract cancers receiving gemcitabine plus capecitabine: a muhicenter, phase II trial of the Swiss Group for Clinical Cancer Research. J Clin Oncol, 2008, 26(22) :3702-3708.
  • 7Sharma A, Dwary AD, Mohanti BK, et al. Best supportive care compared with chemotherapy for unresectable gall bladder cancer: a randomized controlled study. J Clin Oncol, 2010, 28(30) :4581-4586.
  • 8Sasaki T, Isayama H, Yashima Y, et al. S-1 monotherapy in patients with advanced biliary tract cancer. Oncology, 2009, 77(1 ) :71-74.
  • 9Lee S, Oh SY, Kira BG, et al. Second-line treatment with a combination of continuous 5-fluorouracil, doxorubicin, and mitomycin-C (conti-FAM) in gemcitabine-pretreated pancreatic and biliary tract cancer. Am J Clin Oncol, 2009, 32(4) :348-352.
  • 10Sasaki T, Isayama H, Nakai Y, et al. Muhicenter phase II study of S-1 monotherapy as second-line chemotherapy for advanced biliary tract cancer refractory to gemcitabine. Invest New Drugs, 2010, in press.

同被引文献14

  • 1Kawada N, Uehara H, Katayama K, et al. Combined brush cytology and stent placement in a single session for presumed malignant bil- iary stricture. J Gastroenterol Hepatol. 2011,26(8):1247-1251.
  • 2Ross AS. Endoscopic retrograde cholangiopancreatography in sur- gically modified gastrointestinal tract. Gastrointest Endose Clin N Am, 2009,19(3):497-507.
  • 3Chu D, Adler DG. Malignant biliary tract obstruction: evaluation and therapy. J Natl Compr Canc Netw. 2010,8(9):1033-1044.
  • 4Isayama H, Nakai Y, Kawakubo K, et al. Endoscopic retrogradecholangiopancreatography for distal malignant biliary stricture. Gastrointest Endosc Clin N Am, 2012,22(3):479-490.
  • 5Garcea G, Ong SL, Dennison AR, et al. Palliation of malignant ob- structive janndice. Dig Dis Sci, 2009,54(6):1184-1198.
  • 6Dunoncean JM, Andriull A, Deviere J, et al. European Society of Gastrointestinal Endoscopy(ESGE) Guideline: prophylaxis of post- ERCP pancreatitis. Endoscopy, 2012,42(6):503-515.
  • 7Gr6nroos JM, Gullichsen R, Laine S, et al. Endoscopic palliation of malignant obstructive jaundice in extremely elderly patients: plastic stent is enough. Minim Invasive Ther Allied Technol, 2010,19(2): 122-124.
  • 8沈洪章,朱家沂,杨传春,杨斌,周鹏,伏亦伟.80岁以上老年人恶性肝外梗阻性黄疸内镜疗效分析[J].中华临床医师杂志(电子版),2012,6(14):4054-4055. 被引量:1
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  • 10刘勇,纪艳超,陈曦海,孙岩岩,翟哲.经内镜胆道金属支架引流术治疗恶性胆道梗阻76例[J].中华消化内镜杂志,2009,26(10):547-548. 被引量:3

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