期刊文献+

汕头地区女性感染人乳头瘤病毒基因类型的分析 被引量:3

下载PDF
导出
摘要 目的:分析汕头地区各年龄段与不同生殖道疾病女性感染人乳头瘤病毒(HPV)基因类型分布状况,为该地区HPV分子流行病学提供依据。方法:利用凯普的基因芯片导流杂交检测技术,对3770例可疑女性患者进行21种HPV基因亚型的检测与分析。结果:HPV阳性检出率28.40%,其中高、低危型检出率分别72.8%与27.2%。多重感染占总体阳性标本的18.75%,不同年龄组的HPV亚型感染检测率差异不同。结论:HPV16、52、58,CP8304是汕头地区HPV感染的主要型别,宫颈癌患者中主要感染亚型为HPV16,CIN患者中主要感染亚型为HPV16、58,多重感染中以双重感染及四重感染为主,20~50岁为汕头地区感染的高峰人群。
出处 《中国社区医师(医学专业)》 2011年第34期222-223,共2页
  • 相关文献

参考文献6

  • 1International Agency For Research om Cancer.Monographs on the evaluation of the carcinogenic risk of chemicals to humans,vol.64.Human papillomaviruses.Inter-national Agency for Research on Cancer,Lyon,France,1995.
  • 2Bosch FX,Lorincz A,Munoz N,et al.The causal rela-tion between human papillomavirus and cervical cancer.J Clin Pathol,2002,55:244-265.
  • 3Almong B,Gamzu R,Kuperminc MJ,et al.Human papillo-mavirus testing in patient follow-up post cone biopsy due to high-grade cervical intraepithelial.Gynecol Oncol,2003,88:345-350.
  • 4Clifford GM,Smith JS,Plummer M,et al.Human papilloma-virus types in invasiver cancer worldwide:a meta-analysis.Br J Cancer,2003,88:63-73.
  • 5乌兰娜,吴瑞芳,周艳秋,刘志红,张礼婕,黄秀浓,杜辉.人乳头瘤病毒基因亚型与宫颈病变的关系[J].中国妇产科临床杂志,2005,6(5):346-350. 被引量:102
  • 6周毅.人类乳头瘤病毒与宫颈癌的相关调查[J].中华医院感染学杂志,2004,14(2):129-129. 被引量:16

二级参考文献6

  • 1[2]Anttila A, Pukkala E, Sderman B, et al.Effect of organized screening on cervical cancer incidence and mortality in Finland, 1963-1995: Recent increase in cervical cancer incidence.Int J Cancer, 1999,83:59-65.
  • 2[3]Walboomers JM, Jacobs MV, Manos MM, et al.Human papillomavirus is a necessary cause of invasive cervical cancer worldwide.J Pathol, 1999, 189:12-19.
  • 3[4]Bosch FX, Manos MM, Munoz N, et al.Prevalence of Human Papillomavirus in cervical cancer: a World Perspective.J of the National Cancer Inst, 1995, 87: 796-802.
  • 4[5]Clifford GM,Smith JS,Plummer M,et al.Human papillomavirus types in invasive cancer worldwide:a meta-analysis.Br J cancer,2003,88:63-73.
  • 5[6]Biedermann K, Dandachi N, Trattner M, et al. Comparison of Real-Time PCR Signal-Amplified In Situ Hybridization and Conventional PCR for Detection and Quantification of Human Papillomavirus in Archival Cervical Cancer Tissue. J Clin. Microbiol,2004,42: 3758-376.
  • 6沈艳红,陈凤,黄曼妮,刘彬,王希霞,赵方辉,李淑敏,李楠,吴令英,戎寿德,章文华,任生达,黄瑞德,乔友林.我国山西省子宫颈癌高发区人乳头瘤病毒感染调查[J].中国医学科学院学报,2003,25(4):381-385. 被引量:121

共引文献113

同被引文献24

  • 1陶萍萍,卞美璐,欧华,陈庆云,李敏,刘军.导流杂交基因芯片技术在人乳头状瘤病毒检测中应用的研究[J].中华妇产科杂志,2006,41(1):43-47. 被引量:132
  • 2陶萍萍,卞美璐,李敏,刘军.HPV多重感染与宫颈病变关系探讨[J].中国妇产科临床杂志,2006,7(2):94-96. 被引量:112
  • 3关素洁.宫颈癌的发病机制及中医药治疗研究进展[J].中医药导报,2007,13(2):95-96. 被引量:10
  • 4Munoz N, Bosch FX, Casellsague X, et al. Against which hu- man papillomavirus types shall we vaccinate and screen the in- ternational perspective. Int J Cancer, 2004,111 (2) .. 278-285.
  • 5Bachtiary B, Obermair A,Dreier B, et al. Impact of multiple HPVDNAinfection on response to treatment and survival in patients recerving radiotherapy for cervical, cancer. Int J Canc- er,2002,102:237-243.
  • 6Anil L, Hormuzd A, Allan H, et al. Human papillomavirus in- fection with multiple types: pattern,of eoinfeetion and risk of cervical disease. J Infect Disease,203(7) :910-920.
  • 7Sandri MT, Riggio D, Salvatici M, et al.Typing of humanpapillo- mavirus in women with cervical lesions:prevalence anddistribution of different genotypes. Journal of Medical Virology, 2009,33 (5): 2065-2069.
  • 8JhonW.sellorsR,SanKaranarayanan.章文华,主译.宫颈上皮内瘤变的阴道镜检查和治疗[M].北京:人民卫生出版社,2005,7(1):14-15.
  • 9Wright TV JR,Denny K,Kuhn L,et al.HPV-DNS testing of self collected vaginal samples compared with cytological screening to detect cervical cancer[J].JAMA,2000,283(1):81-86.
  • 10章文华.宫颈癌筛查方法与我国宫颈癌筛查面临的新问题[J].中华肿瘤杂志,2008,30(12):881-884. 被引量:76

引证文献3

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部