摘要
通过X射线单晶衍射表征了一种1,10-菲啰啉铒稀土配合物[Er(NO3)3(phen)2],并研究了1,10-菲啰啉及其配合物的抑菌活性.利用紫外光谱、荧光光谱和黏度法研究了配合物与DNA的相互作用.结果表明,配合物以沟槽和部分插入等多种方式与DNA作用.
A rare earth complex[Er(NO3)3(phen)2] was synthesized and characterized by single-crystal X-ray diffraction.The antibacterial activities of phen and the complex have been investigated.The interaction between the complex and DNA has been studied by electronic absorption spectroscopy,fluorescence spectroscopy and viscosity measurements.All results indicated that the interaction mode of the complex and DNA includes groove binding and partial intercalation.
出处
《东北师大学报(自然科学版)》
CAS
CSCD
北大核心
2011年第4期88-91,共4页
Journal of Northeast Normal University(Natural Science Edition)
基金
国家杰出青年科学基金资助项目(20425101)
南京林业大学引进高层次留学回国人员科研基金资助项目
南京大学配位化学重点实验室开放基金资助项目
江苏省高校优势学科建设工程资助项目
关键词
铒配合物
抑菌活性
DNA
erbium complex
antibacterial activity
DNA