摘要
目的:探讨2型糖尿病视网膜病变(DR)的相关危险因素。方法:对562例2型糖尿病患者行眼底检查,测血压,化验FPG、HBA1c、Cr、尿微量白蛋白排泄率(UAER)等指标并进行分析。结果:2型糖尿病患者DR患病率19.2%,其中非增生性DR16.1%,增生性DR3.1%。DR患者的病程、SBP、FPG、HBA1c、Cr、尿微量白蛋白排泄率(UAER)均高于单纯DM患者(P<0.05)。增生性DR患者病程明显长于非增生性DR患者(P<0.01)。Logistic多元回归分析显示病程、HBA1c、UAER是DR发病的独立危险因素。结论:DR与糖尿病病程、SBP、FPG、HBA1c、Cr、UAER等升高有关,病程、HBA1c、UAER是DR发病的独立危险因素。
Objective:To study the risk factors for type 2 diabetic retinopathy(DR).Methods:Eye ground,systolic blood pressure(SBP),fasting blood glucose(FBG),glycosylated hemoglobin(HBA1c),serum creatinine(Cr),urinary albumin excret ratio (UAER)in 562 diabetes were analyzed.Results:The all rate of DR was 19.2%(108/562),including 16.1%(91/562) of non-proliferative DR and 3.1%(17/562) of proliferative DR.The course of disease,SBP,FPG,HBA1c,Cr,UAER in DR were predominantly higher than in NDR(P〈0.05).The course of disease in proliferative DR was obviously higher than in non-proliferative DR(P〈0.01).Logistic multiple regression analysis indicated that The course of disease,HBA1c and UAER were independent risk factor for DR.Conclusion:The DR is correlated with the course of disease,SBP,FPG,HBA1c,Cr and UAER.The course of disease,HBA1c and UAER were independent risk factor for DR.