摘要
目的:探讨经胃镜氩离子凝固术(APC)联合奥美拉唑治疗Barrett食管(BE)的临床疗效及安全性。方法:选择经胃镜检查及病理确诊的17例BE患者进行45周APC治疗,术后予奥美拉唑抑酸治疗,并评估其疗程、疗效及并发症。结果:17例患者经APC治疗均完全消除Barrett黏膜,治疗次数19次,1次15例,2次2例。治疗后2例出现胸骨后疼痛,口服奥美拉唑1周后症状缓解,未出现穿孔、出血、狭窄、感染等严重并发症。17例患者均完成1年随访,3例复发,复发病例均进行第2次治疗,随访6个月未复发。结论:经胃镜氩离子凝固术(APC)联合奥美拉唑治疗Barrett食管安全、有效。
Objective：To explore the clinical effects and safty of argon plasma coagulation（APC）conbined with Omeprazole on Barrett esophagus（BE）.Methods：Seventeen patients who were diagnosed as BE by endoscopy and pathology,underwent 45w APC and omeprazole.The curative effects and complications were evaluated.Conclusions：Endoscopic APC combined with Omeprazole in the treatment of BE is safe,effective and worth dissemination.
