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110例急性冠脉综合征的治疗分析 被引量:1

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摘要 目的探讨急性冠脉综合征(ACS)的有效治疗方法。方法将110例ACS患者随机分成对照组和观察组各55例,对照组采用常规治疗方法,观察组在对照组治疗方法基础上加服氯吡格雷与氟伐他汀。结果对照组显效12例,有效8例,总有效率36.4%;观察组显效26例,有效19例,总有效率81.8%。经统计学处理,观察组的总有效率显著高于对照组(P<0.05)。对照组共发生心血管事件33例,其中心血管死亡6例、复发性心绞痛18例、非致死性心梗9例,心血管事件发生率为60%(33/55)。观察组共发生心血管事件10例,其中复发性心绞痛7例、非致死性心梗3例,无死亡病例、心血管事件发生率为18.2%(10/55)。经统计学处理,观察组心血管事件的发生率明显低于对照组(P<0.01)。两组不良反应相比较,差异无统计学意义(P>0.05)。结论在常规治疗方法的基础上加服氯吡格雷与氟伐他汀治疗ACS具有安全、疗效显著等特点,能明显降低血脂、减少心肌缺血/再灌注损伤、抗炎、改善内皮细胞功能、稳定斑块并更有效的降低血小板聚集,减少心血管事件的发生,是ACS的有效治疗方法。
出处 《中国实用医药》 2011年第32期81-82,共2页 China Practical Medicine
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