大叶醉鱼草黄酮类成分研究

Study on the Flavanone Constitutes of Buddleja davidii

目的:对大叶醉鱼草化学成分进行研究。方法:利用硅胶柱色谱、聚酰胺柱色谱、大孔吸附树脂进行分离纯化,并运用现代波谱技术进行结构鉴定。结果:从大叶醉鱼草地上部分分离得到7个黄酮类化合物,分别鉴定为:洋芹素(1)、洋芹素-7-O-β-D-葡萄糖苷(2)、金合欢素(3)、金合欢素-7-O-β-D-葡萄糖苷(4)、金合欢素-7-O-α-L-鼠李糖(1-6)-β-D-葡萄糖苷(5)、木犀草素(6)、木犀草素-7-O-β-D-葡萄糖苷(7)。结论:所有化合物均为首次从该植物中分离得到。

Objective ：To study the chemical constitutes of Buddleja davidii. Methods：The constitutes were isolated and purified by silica gel column chromatography, polyamide column chromatography and macroporous absorption resin and their structures were eluci- dated by spectroscopic analysis. Results： Seven compounds including Apigenin （ 1 ）, Apigenin-7-O-β-D-glucoside （ 2 ）, Acacetin （ 3 ）, Acacetin-7-O-β-D-glucoside （4）, Acacetin-7-O-a-L-rhamnopyranosyl- （ 1-6 ） -β-D-glucopyranoside （ 5 ）, Luteolin （ 6 ）, Luteolin-7-O-β-D- glueoside （7）. Conclusion： All these compounds are obtained from this plant for the first time.