布地奈德联合沙丁胺醇雾化吸入治疗毛细支气管炎疗效观察

The Clinical Efficacy of Inhaled Budesonide Combined with Salbutamol in the Treatment of Bronchiolitis

目的:探讨布地奈德联合沙丁胺醇雾化吸入治疗毛细支气管炎的临床疗效。方法:80例毛细支气管炎患儿随机分为两组各40例。两组均给予抗病毒、吸氧、止咳、镇静对症治疗,治疗组在此基础上加用布地奈德1 mg和沙丁胺醇2.5 mg氧气驱动雾化吸入2,次/d,疗程为3～7 d。结果:治疗组显效率90.0%,总有效率97.5%;对照组显效率70.0%,总有效率90.0%,治疗组显效率明显高于对照组,两组比较差异有统计学意义(P<0.05)。结论:布地奈德联合沙丁胺醇雾化吸入治疗毛细支气管炎疗效显著,安全性好。

Objective： To study the clinical efficacy of inhaled budesonide combined with salbutamol in the treatment of bronchiolitis.Methods： Eighty cases of bronchiolitis were randomly divided into two groups.Both groups received symptomatic treatment,such as anti-virus,oxygen inhalation,cough stop and sedation.In addition to symptomatic treatment,the treatment group was given budesonide 1 mg and salbutamol 2.5 mg with the oxygen-driven inhalation,2 times a day and treatment course for 3 to 7 days.Results：Treatment efficiency and the total effective rate in the treatment group were 90.0% and 97.5% respectively,while those were 70.0% and 90.0% in the control group.The efficiency in the treatment group was significantly higher than that in the control group and the difference was significant（P0.05）.Conclusions： Inhaled budesonide combined with salbutamol in the treatment of bronchiolitis is effective and safe.