三种用药方案治疗小儿轮状病毒肠炎的成本-效果分析

Cost-effectiveness Analysis of Three Medication Regimens for Rotavirus Enteritis in Children

目的:探讨三种方案治疗小儿轮状病毒肠炎的临床疗效及经济学效益。方法:采用回顾性调查方法,分别对常规治疗(A组)、利巴韦林(B组)、热毒宁注射液(C组)治疗小儿轮状病毒肠炎进行疗效评价,并进行成本-效果分析。结果:A、B、C组总有效率分别为65.71%8、1.08%9、3.75%(χ2=9.793,P<0.05),总成本分别为641.0、670.5、873.0元,成本-效果比分别为975.5、827.09、31.2,B、C组增量成本-效果比分别为191.9、816.9。结论:B方案治疗小儿轮状病毒肠炎较佳。

Objective： To evaluate the clinical efficacy and cost-effectiveness of three medication regimens in the treatment of rotavirus enteritis in children.Methods： Using a retrospective study,the curative efficacy and the cost-effectiveness analysis were performed on the following three regimens in treating rotavirus enteritis in children： conventional treatment（Group A）,Ribavirin（Group B）,and Reduning injection（Group C）.Results： The total effective rate of the three schemes were 65.71%,81.08% and 93.75%,the total costs were 641.0,670.5 and 873.0 RMB,and the ratios of cost-effectiveness were 975.5,827.0 and 931.2,respectively.Compared with Group A,the incremental cost-effective ratios for B and C groups were 191.9 and 816.9.Conclusions： Group B（Ribavirin） is the optimal regimen among the three groups for children with rotavirus enteritis.