摘要
目的:探讨肺开放治疗对体外循环(cardiopulmonary bypass,CPB)术后急性肺损伤(acute lung injury,ALI)婴儿血流动力学和呼吸力学的影响。方法:随机选取2008年3月~2010年7月西京医院心血管外科接受心脏手术的64例ALI婴幼儿,分为无肺复张治疗组(非肺复张组):采用小潮气量通气模式进行呼吸辅助及治疗,肺复张治疗组(肺复张组):在小潮气量通气模式下,加用肺开放治疗(lung recruitment maneuver,LRM)。结果:在肺复张治疗后,呼吸力学和氧合都有显著的改善,肺复张组的PaO2[(284±19)mmHg]明显高于非肺复张组[(78±18)mmHg](P<0.01)。肺复张组的呼吸力学指标显著优于非肺复张组,血流动力学指标无显著性差异。结论:LRM可以大大改善婴儿CPB术后ALI的氧合及呼吸力学。
AIM: To investigate the effects of open lung ventilation on the haemodynamics and respiratory mechanics in infants with acute lung injury(ALI) after cardiopulmonary bypass(CPB).METHODS: Sixty-four infants with ALI undergoing open-heart surgery were randomized into Group A of no-lung recruitment maneuver(N-LRM),with only low tidal volume,and Group B of lung recruitment maneuver(LRM),with low tidal volume and lung recruitment maneuver remedy.RESULTS: The oxygenation was remarkably improved after LRM in group B.PaO2 in Group B was significantly higher than that in group A [(284±19) mmHg vs.(78±18) mmHg,P 0.01] and the respiratory mechanics in group B was superior to those in group A.No significant difference was observed in the haemodynamics between the two groups.CONCLUSION: LRM improves the oxygenation and the respiratory mechanics but has no obvious side effect on haemodynamics in infants with ALI after cardiopulmonary bypass.
出处
《心脏杂志》
CAS
2011年第6期798-800,803,共4页
Chinese Heart Journal
关键词
肺开放
新生儿
急性肺损伤
体外循环
血流动力学
open lung
infants
acute lung injury
cardiopulmonary bypass
hemodynamics