复方樟柳碱联合体外反搏治疗视神经挫伤的效果

The therapeutic efficacy of combined treatment of compound anisodin and external counter pulsation for the optic nerve contusion.

目的探讨复方樟柳碱颞浅动脉旁注射联合体外反搏治疗视神经挫伤的效果。方法视神经挫伤55例（60眼）分为3组：常规药物组17例（20眼），应用常规药物治疗；复方樟柳碱组20例（20眼），除常规药物外，加用复方樟柳碱2ml患侧颞浅动脉旁皮下注射，1次／d。疗程14d；体外反搏组18例（20眼），除用以上两组治疗方法外，加用体外反搏治疗。疗效主要观察指标是视力、视野、视觉诱发电位。结果常规药物组有效率为35％，樟柳碱组有效率为70％，体外反搏组有效率为85％。两两比较，差异有统计学意义（P〈0．05）。结论颞浅动脉旁皮下注射复方樟柳碱联合体外反搏治疗视神经挫伤有明显疗效。

Objective To investigate the efficacy of the combined therapy for the optic nerve contusion by subcutaneous injecting compound anisodine near the superficial temporal artery and external counter pulsation （ECP）. Methods Sixty eyes of 55 cases of optic nerve contusion were divided into three groups. Taking 17 patients （20 eyes） as a regular medicine treating group. Another 20 patients （20 eyes） as a compound anisodine injection treating group, subcutaneous injecting of 2 ml compound anisodine near the superficial temporal artery was done together with medicine treatment. One injection a day, 14 days as one course. The other 18 patients （20 eyes） as ECP treating group, in which ECP was applied besides compound anisodine injection and medicine treatment. The treatment effect was evaluated by 3 elements： visual acuity, visual field and VEP. Results The total efficiency of the ECP treating group was 85% while the medicine treating group only got 35% and the compound anisodine injection group got 70%. There was distinct statistical difference between each other in the three groups （P 〈 0.05）. Conclusion The combined treatment of the subcutaneous injecting compound anisodine and ECP has significant effect on the optic nerve contusion.