LASIK手术对眼脉动振幅的影响

Effect of the LASIK on the ocular pulse amplitude

目的通过对准分子激光原位角膜磨镶术(LASIK)手术前后眼脉动振幅(OPA)值的对比分析,探讨LASIK手术对眼底血液循环的影响。方法对行LASIK手术的97例(185只眼)患者于术前和术后1个月用Pen-tacam系统测量中央角膜厚度(CCT)和角膜曲率(CCV)后,用动态轮廓眼压计进行眼压(IOP)和OPA测量,将测量结果进行统计学分析。结果眼压值在手术前后无显著性差异(P>0.05),而OPA值在术后1个月低于术前,手术前后差异有统计学意义(P<0.01)。OPA值术前和眼压值无相关性(P>0.05),术后与眼压值呈正相关(P<0.01);术前和术后OPA值与CCT、CCV均无相关性(P>0.05)。结论 LASIK手术对眼压影响不明显,但使OPA值降低,OPA值降低的原因有待进一步研究。

Objective To evaluate the effect of laser in situ keratomileusis(LASIK) on retinal blood circulation by comparing and analyzing the ocular pulse amplitude(OPA) values before and after LASIK.Methods After measured central corneal thickness(CCT) and corneal curvature(CCV) by Pentacam system,97 patients(185eyes) which would be treated by LASIK operation were measured intraocular pressure(IOP) and OPA by the dynamic contour tonometry(DCT) before operation and one month after operation,Finally the statistical analysis were adopted to evaluate the measurement results.Results There was no statistical difference between the IOP values before and after LASIK(P > 0.05),The values of OPA one month after operation were lower than that before operation and there had significant difference between the two group data(P < 0.01).Before operation the OPA values had no correlation with the IOP values(P > 0.05),but they had positive correlation after LASIK(P < 0.01).Both the CCT and CCV had no influences on the OPA values before and after LASIK(P > 0.05).Conclusion The LASIK didn't affect the IOP obviously,but it could make the OPA value decline.The reason why the OPA value decreased needed further study.