新生儿围手术期的营养支持

Nutrition support for neonates in perioperative period

目的评估新生儿围手术期应用胃肠外营养(PN)支持的临床疗效,为营养支持的合理运用提供依据。方法对30例围手术期新生儿进行营养评估,营养不良者在肠内营养的基础上辅以PN,总结PN的组成、供给量、配制顺序、使用途径,并监测体质量、实验室指标、预后及防治并发症。结果 30例病例中,26例痊愈,4例好转。PN治疗后,患儿体质量、血浆白蛋白较前略有增加(P均<0.05),肝转氨酶、黄疸、血脂、尿素氮、前白蛋白、总胆汁酸均无明显变化。结论 PN支持方案安全、有效,实施方便;对于蛋白质营养不良新生儿围手术期的PN支持,应适当增加氨基酸的供给量。

Objective To summarize the clinical therapeutic effects of parenteral nutrition（PN）support on 30 neonates in their perioperative period of abdominal surgery,and to get the basis of reasonable nutrition support.Methods The nutritional status of 30 neonates were estimated in perioperative period and were given PN if malnutrition.The component,dose,preparation and administration of PN were summarized.The weight,laboratory data and prognosis were monitored before and after PN support,meanwhile complications were prevented.Results Twenty-six cases were cured and 4 cases were improved.Patients＇weight and plasma-albumin were raised lightly after PN treatment（P 0.05）with no change of blood aminopherase,bilirubin,lipid,urea nitrogen,prealbumin and total bile acid.Conclusions The nutrition support is effective,safe and easy to undertake.Amino acids should be increased if PN is applied to neonates with protein malnutrition.