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他汀类药物安全性再认识 被引量：5

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摘要 大量研究奠定了他汀类药物在心血管疾病一级和二级预防中不可动摇的地位．强化调脂的理念已经深入临床。大剂量他汀类药物治疗对肝脏和肌肉潜在的不良反应已得到医患的重视，而近年来对他汀类药物肾脏损害、神经系统不良反应、新发肿瘤和糖尿病等的担忧和争论始终没有停止。因此，
作者 边素艳 叶平
机构地区 中国人民解放军总医院老年心血管二科
出处 《内科理论与实践》 2011年第6期416-420,共5页 Journal of Internal Medicine Concepts & Practice
关键词 他汀类药物 安全性 心血管疾病 糖尿病 肿瘤
分类号 R972.6 [医药卫生—药品]
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参考文献10

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同被引文献89

  • 1杜瑞雪,叶平.2011年欧洲血脂异常管理指南解读[J].中国医学前沿杂志（电子版）,2011,3(4):87-90. 被引量：9
  • 2杨士杰,李栋,姜达.辛伐他汀对荷瘤小鼠抑瘤作用的实验研究[J].河北医药,2006,28(7):573-574. 被引量：3
  • 3郭丽萍,罗建民.P21蛋白和生存素在美伐他汀诱导人非小细胞肺癌凋亡中的作用[J].解放军医学杂志,2006,31(9):873-875. 被引量：1
  • 4中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量：5224
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  • 6Sassano A, Platanias LC. Statins in tumor suppression[J]. Cancer Lett,2008,260(1 2) : 11-19.
  • 7Wong WW, Dimitroulakos J, Minden MD, et al. HMG-CoA reductase inhibitors and the malignant cell: the statin family ofdrugs as triggers of tumor-specific apoptosis[J]. Leukemia. 2002,16(4) : 508-519.
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  • 10Dale KM, Coleman CI, Henyan NN, et al. Statins and cancer risk: a meta-analysis[J]. JAMA,2006,295(1):74-80.

引证文献5

二级引证文献7

内科理论与实践
2011年 第6期

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