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胰腺星状细胞与胰腺癌关系的研究进展 被引量:2

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摘要 胰腺癌多源于胰腺导管上皮,恶性程度高、预后差,5年生存率不超过1%。在西方国家,胰腺癌占恶性肿瘤死因的第4位,年发病率约为10/10万。肿瘤从正常导管上皮、导管上皮内瘤变发展至浸润性导管癌的发病模式提示一系列原癌及抑癌基因在其中的作用,既往的研究多关注肿瘤细胞本身,近年来肿瘤微环境对肿瘤发生、发展的影响日益受到关注。
出处 《中华普通外科杂志》 CSCD 北大核心 2011年第12期1057-1059,共3页 Chinese Journal of General Surgery
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