长沙市开福区甲型H1N1流感大流行与肺炎发病的相关性

Analysis of correlation of pandemicof influenza A(H1N1) with pneumonia in Kaifu District of Changsha City

目的分析长沙市开福区甲型H1N1流感大流行期间疫情情况,了解大流行对肺炎的影响,为评估流感大流行影响提供科学依据。方法系统收集大流行期间开福区辖区内甲型H1N1流感病例资料,按月份收集住院患者总数、肺炎病例数、重症肺炎病例数、因重症肺炎死亡数,采用Pearson相关进行甲型H1N1流感与各类肺炎发病与死亡的月份直线相关关系分析。结果流感大流行在开福区历时10个月,流行主要集中在2009年9月～2010年1月的4个月时期内。全球大流行期间,开福区肺炎患者占住院患者的5.59%,重症肺炎病例占肺炎总数的4.49%,重症肺炎病死率为4.21%。甲型H1N1流感与肺炎、重症肺炎、因重症肺炎死亡的相关系数分别为0.536、-0.338、0.505,仅前者存在统计学意义,后两者无统计学意义。开福区大流行期间肺炎百分比高于对照期间的肺炎百分比。结论甲型H1N1流感大流行可能引起肺炎病例增加,但对重症肺炎及其死亡影响不大。

Objective To understand the situation of pandemics of influenza A（H1N1）in Kaifu District of Changsha and its impact on pneumonia.Methods The data of influenza A（H1N1）cases inpatients with pneumonia in the pandemic period in Kaifu District were collected,the mortality of pneumonia inpatients associated with influenza A（H1N1）and severe pneumonia were also collected on monthly basis and analyzed.Results The pandemic of influenza A（H1N1）lasted for 10 months in Kaifu District.In the pandemic period the inpatients with pneumonia accounted for 4.49% of total inpatients,and the mortality of inpatients with severe pneumonia was 4.21%.The correlation coefficients of influenza A（H1N1）cases with pneumonia inpatients,severe pneumonia cases died due to severe pneumonia were 0.536,-0.338 and 0.505,respectively.Conclusion The pandemic of influenza A（H1N1）may cause the increase of number of inpatients with pneumonia,but has little impact on the incidence and mortality of inpatients with severe pneumonia.