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胰岛素与多囊卵巢综合征高雄激素血症的新研究进展 被引量:4

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摘要 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是最常见的内分泌疾病之一,它影响6%一10%生育年龄的妇女[1]。在2003年鹿特丹修订PCOS的诊断标准认为排除其他雄激素过多的相关疾病后符合以下3条标准中的2条即可诊断为PCOS:①稀发排卵和/或不排卵;②临床和/或生化高雄激素血症的表现;③多囊性卵巢的形态。而2006年,高雄激素血症.多囊卵巢综合征社会工作组决议认为,PCOS应首先考虑是雄激素过多的疾病或高雄激素血症。在2009年该组织根据现有数据提出了一个新的PCOS定义,即PCOS应通过高雄激素血症的表现(临床和/或生化),卵巢功能障碍(稀发排卵一无排卯和/或多囊样卵巢)以及排除相关的疾病来定义[2]。
出处 《中华内分泌外科杂志》 CAS 2011年第6期421-423,共3页 Chinese Journal of Endocrine Surgery
基金 国家公益性行业慢病专项(201107005) 国家发改娄/中医药管理局,国家中医临床研究基地(月经病)建设项目[国中医药发(2008)23号]
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参考文献22

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同被引文献62

  • 1梁诗莹,赵萍.卵巢储备功能的超声研究进展[J].中华医学超声杂志(电子版),2013,10(8):603-611. 被引量:11
  • 2游凯.多囊卵巢综合征患者的血脂异常及其处理要点[J].中华妇产科杂志,2007,42(10):716-718. 被引量:7
  • 3Teede H,Deeks A,Moran L.Polycystic ovary syndrome:a complex condition with psychological,reproductive and metabolic manifestations that impacts on health across the lifespan[J].BMC Med,2010,8:41.
  • 4Freeman R,Pollack R,Rosenbloom E.Assessing impaired glucose tolerance and insulin resistance in Polycystic Ovarian Syndrome with a muffin test:an alternative to glucose tolerance test[J].Endocr Pract,2010,16 (5):810-817.
  • 5Farrell K,Antoni MH.Insulin resistance,obesity,inflammation,and depression in polycystic ovary syndrome:biobehavioral mechanisms and interventions[J].Fertil Steril,2010,94(5):1565-1574.
  • 6Sharma ST,Nestler JE.Prevention of diabetes and cardiovascular disease in women with PCOS:treatment with insulin sensitizers[J].Best Pract Res Clin Endocrinol Metab,2006,20 (2):245-260.
  • 7Pasquali R,Gambineri A,Pagotto U.The impact of obesity on reproduction in women with polycystic ovary syndrome[J].B JOG,2006,113(10):1148-1159.
  • 8Bhathena RK.Therapeutic options in the polycystic ovary syndrome[J].J Obstet Gynaeco1,2007,27 (2):123-129.
  • 9Glintborg D,Andersen M.An update on the pathogenesis,inflammation,and metabolism in hirsutism and polycystic ovary syndrome[J].Gynecol Endocrinol,2010,26(4):281-296.
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