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不同龋敏感儿童变异链球菌临床分离株耐酸能力的实验研究 被引量：2

Study on the ability of aciduricity of Streptococcus mutans isolated from children with different caries susceptibility
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摘要 目的:比较不同龋敏感儿童口腔中变异链球菌临床分离株耐酸能力的差异。方法:以高龋、中龋和无龋儿童口腔中分离得到的变异链球菌为实验菌株,以ATCC25175国际标准株作对照,经常规复苏、增菌后,配制相同浓度的菌悬液,pH在7.0～6.0时各菌株间的耐酸能力无显著差异(P>0.05),而当pH在5.5～5.0时,分别在不同pH(以0.5为间隔,pH 4.0～7.0)的BHI液体培养基中培养48 h后,用紫外分光光度计在540 nm处测定吸光度,比较细菌的生长情况。结果:高、中龋病人口腔中分离出的变异链球菌临床分离株和国际标准菌株的耐酸能力明显高于无龋者口腔中分离出的变异链球菌,差异具有统计学意义(P<0.05)。结论:高龋儿童口腔中变异链球菌临床分离株具有高致龋性。 AIM： To investigate the aciduricity of Streptococcus mutans isolated from children with different caries susceptibility.METHODS： The aciduric ability of Streptococcus mutans strains isolated from children was measured.Different acidogenicity was compared among high caries-susceptible group,middle caries-susceptible group and caries-free group.RESULTS： The aciduricities of Streptococcus mutans isolated from the high caries-susceptible children and middle caries-susceptible group were significantly higher than that isolated from caries-free group（P0.05）.CONCLUSION： The high cariogenecity of Streptococcus mutans strains isolated from caries-active children shows a close relationship with the high aciduricity of the isolated Streptococcus mutans strains.
作者 曹元书 刘兴容
机构地区 泸州医学院附属口腔医院
出处 《牙体牙髓牙周病学杂志》 CAS 北大核心 2011年第12期691-693,共3页 Chinese Journal of Conservative Dentistry
关键词 变异链球菌 龋敏感 致龋性 耐酸 Streptococcus mutans caries sensitive cariogenicity aciduricity
分类号 R780.2 [医药卫生—口腔医学]
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参考文献11

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二级参考文献16

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共引文献10

同被引文献19

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牙体牙髓牙周病学杂志
2011年 第12期

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