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药物代谢酶和药物转运体基因多态性与儿童急性淋巴细胞白血病化疗 被引量:2

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摘要 目的:介绍药物代谢酶和药物转运体基因多态性与儿童急性淋巴细胞白血病化疗关系的研究进展。方法:查阅相关文献,并对其进行分析、归纳、总结。结果与结论:药物代谢酶和药物转运体基因多态性可以影响儿童急性淋巴细胞白血病化疗药物的药动学和药效学参数,与治疗药物的效应及毒副作用之间存在一定的相关性,但离将这些多态性位点的基因型作为儿童急性淋巴细胞白血病化疗决策的依据尚有一定距离。
作者 许静 徐康康
出处 《中国药房》 CAS CSCD 2012年第2期159-162,共4页 China Pharmacy
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参考文献24

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二级参考文献15

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