海洋放线菌代谢产物蒽环类化合物研究进展

Research Progress in Anthracycline Compounds Produced by Marine Actinomycetes

海洋放线菌代谢产物是抗肿瘤活性物质的重要来源。近年来,从海洋放线菌中分离到很多新化合物,其中许多结构新颖的蒽环类代谢产物具有良好的抗菌抗肿瘤活性。文章对近年来从海洋放线菌中分离得到的蒽环类代谢产物进行了归纳,并展望今后海洋天然产物的发展方向。

The marine actinomycetes are likely to be important sources of new natural products. In recent years, plenty of novel structares have been isolated from marine actinomyeetes. Among them, there are many novel anthracycline metabolites with good antibacterial and antitumor activities. Anthracycline compounds isolated from marine actinomycetes and their activities were summarized in this paper, and a perspective in regard to the future development of the marine natural products was also discussed.