曲美布汀联合乌灵胶囊治疗功能性消化不良的疗效观察

Observation the efficacy of trimebutine combined with willing capsule in the treatment of functional dyspepsia

目的观察曲美布汀联合乌灵胶囊治疗功能性消化不良(FD)的疗效。方法选取150例FD患者随机分为两组,观察组80例,给予曲美布汀胶囊及乌灵胶囊联合用药治疗;对照组70例,单用曲美布汀治疗。比较观察两组的上腹胀满、餐后饱胀、早饱等症状的变化情况。结果观察组的疗效优于对照组(P<0.01),总有效率(88.8%)也高于对照组(55.7%)(P<0.01)。两组患者均无严重的不良反应,两组不良反应发生率比较差异无统计学意义(P>0.05)。结论曲美布汀联合乌灵胶囊治疗FD疗效好、耐受性好,是一种可靠可行的治疗FD的方案。

Objective To study the efficacy of trimebutine and wuling capsule in the treatment of functional dyspepsia（FD）. Methods One hundred and fifty FD patients were randomly divided into two groups. The observation group（n = 80） were given 100mg trimebutine （3 times a day） and 0. 99 g wuling capsule（3 times a day） ; The control group （n =70） were given 100 mg trimebutine （3 times a day ） ,for 8 weeks. Clinical symptoms were com- pared. Results The total effective rates were 88.8% and 55. 7% in observation group and control group, respectively. The difference between two groups was significant （ P 〈 0. 05）. There was no severe side effect in two groups. Conclusion The therapeutic effect of trimebutine combined with waling capsule in treating FD is satisfactory and safe.