近无毛灰岩香茶菜的研究

STUDY ON THE RABDOSIA CALCICOLUS VAR. SUBCALVUS

从云南省会泽县产近无毛灰岩香茶莱〔Rabdosia calcicola (Hand. -Mazz.) Hara var. subculva (Hand. -Mazz.) C. Y. Wu et H. W. Li〕叶中分得两个二萜化合物,一个为新化合物,命名为灰岩香茶菜甲素(calcieolin A),另一个为已知化合物维西香茶菜甲素(weisiensin A),经各项光谱数据和化学反应确定,灰岩香茶菜甲素为3β-羟基-1α,6α,7β,11β-四乙酰氧基-对映-贝壳杉-16-烯-15-酮(1);维西香茶菜甲素结构应为3β,6α-二羟基-1α,7β,11β-三乙酰氧基-对映—贝壳杉-16-烯-15酮(2)。

Two diterpenoids were isolated from the leaves of Rabdosia calcicolus var. subcalvus Hand. -Mazz. Weisiensin A is a known compound, ils strueturc should be corrected to 3β, 6α-dihydroxy-1α, 7β, 11β-triacetoxy-cut-kaur-16-en--15-one by spectro-scopic and chemical evidences. Calcicolin A is a new diterpenoid, its structure was established as 3β-hydroxy-1α,6β,7β, 11β-tctraacetoxy-ent-kaur-16-en-15-one (1) on the basis of spectral data.