氟康唑联合乳酸杆菌活菌制剂用于外阴阴道假丝酵母菌病疗效

Curative effects of Fluconazole combined with Viable Lactobacillus Preparation in treatment of vulvovaginal candidiasis

目的:探讨氟康唑联合乳酸杆菌活菌制剂在外阴阴道假丝酵母菌病治疗中的临床意义。方法:将我院经治的外阴阴道假丝酵母菌病80例,随机分为实验组和对照组,实验组应用氟康唑联合乳酸杆菌活菌制剂治疗,对照组单纯应用氟康唑治疗,观察两组的治疗效果。结果:在实验组中有29例治愈,治愈率为72.5%,对照组为23例,治愈率为57.5%,两者比较差异有统计学意义(P<0.05);在实验组中40例患者治疗均有效,有效率达100%,对照组中35例治疗有效,有效率达87.5%,两者比较差异有统计学意义(P<0.05)。结论:氟康唑联合乳酸杆菌活菌制剂在治疗外阴阴道假丝酵母菌病方面,和单纯的抗真菌治疗比较,可以获得更加理想的治疗效果,有效减轻患者的痛苦,值得在临床中广泛使用并推广。

Objective：To investigate the clinical significance of Fluconazole combined with Viable Lactobacillus Preparation in the treatment of vulvovaginal candidiasis.Methods：80 patients with vulvovaginal candidiasis treated in our hospital were randomly divided into the experimental group and the control group.The experimental group was treated with Fluconazole combined with Viable Lactobacillus Preparation and the control group was treated with Fluconazole only.The curative effects of the two groups were observed.Results：In the experimental group,29 patients were cured,with the cure rate of 72.5%,and in the control group,23 patients were cured,with the cure rate of 57.5%.The difference between the two groups was statistically significant（P〈0.05）.In the experimental group,40 patients had valid curative effects,with the effective rate of 100%,and in the control group,35 patients had valid curative effects,with the effective rate of 87.5%.The difference between the two groups was statistically significant（P〈0.05）.Conclusion：Compared with the simple anti-fungal treatment,Fluconazole combined with Viable Lactobacillus Preparation can obtain more preferable curative effects and effectively reduce the pain of patients in the treatment of vulvovaginal candidiasis,thereby worthy of clinical application and promotion.