静脉输注高氧液治疗颅脑外伤的临床疗效分析

The Clinical Analysis of Intravenous Infusion of High-oxygen Liquid Treatment on Patients with Traumatic Brain Injury

目的观察高氧液治疗重型颅脑损伤的疗效。方法 42例患者随即分为治疗组和对照组,治疗组在对照组常规治疗的基础上加高氧液治疗;高氧液(500～1000mL)常规静脉滴注,共10d。再分别做第1天、第10天的GCS(格拉斯哥昏迷评分),以GCS及血氧饱和度(SPO2)判断疗效并作统计学处理,治疗期间注意对比血氧饱和度的变化。结果治疗组和对照组GCS评分在治疗第一天差异无统计学意义(P>0.05),第十天差异有统计学意义(P<0.05)。血氧饱度在输注高氧液5～10min有少许提高,但输注前后有明显差异(详见统计表)。结论对照组病死率20%,治疗组病死率9%,两组差异有统计学意义(P<0.05)。结论高氧液对重型颅脑损伤的治疗有较好的促进作用,能有效提高机体氧含量,并降低后期病死率。

Objective To observe the efficacy of treatment on patients of severe head injury with the high-oxygen liquid. Methods 42 patients were randomly divided into treatment group and control group, treatment group was received with conventional treatment, adding to the application of high- oxygen liquid therapy; the high-oxygen solution （500~1000mL） was infused through conventional intravenous for 10 days. And then the GCS （Glasgow Coma Scale） were done on the first day and tenth day, GCS and oxygen saturation （SPO2） were used to made the statistical analysis and to determine efficacy of treatment, the changes of oxygen saturation was compared during the time. Results The GCS has no significant difference on the first day between treatment and control groups （P〉0.05）, but there was significant difference on the tenth day （P〈 0.05）. 19.05% and 9.52% were the mortalities in the control group and treatment ones, the difference was statistically significant （P〈0.05）. Conclusion High-oxygen liquid can promoted greatly the treatment on patients with severe head injury, which can improve the body＇s oxygen content, and lower the mortality.