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肠杆菌科细菌耐碳青霉烯类抗菌药物耐药机制的研究进展 被引量:5

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摘要 碳青霉烯类药物由于其良好的细胞通透性及高度的酶稳定性,是治疗产超广谱β-内酰胺酶(ESBLs)和AmpC酶革兰阴性杆菌感染的有效抗菌药物,对肠杆菌科细菌有非常强的抗菌活性,但随着临床的广泛应用,临床已出现了对其耐药的肠杆菌科细菌,且不断有新的耐药基因被发现。本文就其耐药机制、检测方法、常用抗菌药物的选择及预防措施等问题作一综述。
出处 《中国微生态学杂志》 CAS CSCD 2011年第12期1148-1149,1152,共3页 Chinese Journal of Microecology
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