急性心肌梗死患者血脂临床分析

The Analysis of Blood Lipids in Patients with Acute Myocardial Infarction

目的了解急性心肌梗死(AM)I患者急性期血脂指标:甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(LDL-C)、低密度脂蛋白胆固醇(HDL-C)的改变以及患者运用他汀类药物的情况.方法采用随机抽样调查住院病历资料的方式,研究206例曾住院治疗的AMI患者(AMI组)和240例未发生AMI的冠心病患者(对照组)的部分血生化指标以及病史;并对部分AMI组患者进行回访调查.结果(1)AMI组TG、TC、LDL-C水平均低于对照组(P<0.05),而HDL-C在两组之间的水平差异无统计学意义(P>0.05);(2)AMI组部分患者经他汀类药物治疗1 a后,除HDL-C增高外,TG、TC、LDL-C均为随治疗时间的增加呈现降低的趋势(P<0.05).结论AMI患者急性期血脂水平较CHD未发生AMI时低;心梗急性期开始坚持运用他汀类药物患者的血脂指标将得到进一步改善.

Objective To study the changes of triglyceride（TG）,total cholesterol（TC）,high density lipoprotein cholesterol（H-DLC）and low density lipoprotein cholesterol（L-DLC）in patients with acute myocardial infarction（AMI）.Methods We studied he data including blood biochemical indicators and disease history of 206 patients with AMI（AMI group）and 240 patients without AMI（control group）by case history random sampling.Some patients with AMI were followed up.Results（1）The blood levels of TG,TC and LDL-C in AMI group were lower than those in the control group（P0.05）,but there was no significant difference in the blood levels of HDL-C between two groups.（2）Except the blood level of HDL-C was higher than that of in acute stage after one year treatment with Stains,the levels of TG,TC and LDL-C were all lower than that of in acute stage（P0.05）.Conclusions The blood levels of TG,TC,LDL-C in AMI patients are lower than those of CHD patients without AMI.The patient＇s blood lipids can be improved if they receive medication of stains.