大理市1起食用螺肉引起的广州管圆线虫病暴发调查

Investigation on outbreak of angiostrongyliasis cantonensis due to consumption of snail food in Dali City

目的调查2011年3月大理市1起嗜酸性细胞增多性脑膜炎暴发的原因。方法对集体进餐的18人进行回顾性调查,对住院病例进行病历资料分析,核实诊断。通过线索调查,对未住院治疗的患者进行个案调查。同时,检测大理市市售福寿螺是否感染广州管圆线虫幼虫。结果 18人中16人进食福寿螺,9人发病,发病率为56.3%;未食螺肉的2人均未发病。7人检测广州管圆线虫抗体,3人阳性,阳性率为42.9%。福寿螺的来源地为集贸市场,而同期福寿螺监测资料显示其感染率达7.3%。结论根据流行病学调查、临床表现、实验室检查,确定此次广州管圆线虫病暴发由食用感染广州管圆线虫的福寿螺肉所致。

Objective To investigate the potential cause of an outbreak of eosinophilic meningitis in Dali City in March, 2011. Methods A retrospective investigation was performed among 18 consumers who had meal together. The clinical documents of inpatients were analyzed and the diagnoses were checked. The outpatients were investigated through a case survey. Pomacea snails on sale were examined for the infection status of Angiostrongylus cantonensis. Results Of 18 persons, 16 consumed Pomacea snail food and 9 were infected with an infection rate of 56.3%. The two persons who did not consumed snail food were not infected. Serum samples of seven patients were examined for antibody to Angiostrongylus cantonensis in peripheral blood and 3 were proved positive （42.9%）. The snails consumed by the patients came from the market, and the surveillance data showed that the infection rate of Angiostrongylus cantonensis of Pomacea snails was 7.3%. Conclusion According to the epidemiological survey, clinical manifestations, and laboratory examinations, the outbreak of eosinophilic meningitis is due to the consumption of Pomacea snails infected with Angiostrongylus cantonensis.