摘要
目的 :通过动物实验验证消炎利胆胶囊的利胆抗炎作用。方法 :按生药 3、6、12 g/kg消炎利胆胶囊口服给药 ,观察大鼠胆汁分泌量以及二甲苯致小鼠耳肿胀 ,醋酸对小鼠血管通透性 ,蛋清致大鼠足肿胀和棉球法引起大鼠肉芽组织增生。结果 :消炎利胆胶囊明显增加胆汁分泌量 ,且随剂量增加而增多 ,维持时间达 4h之久 ;抑制二甲苯致小鼠耳肿胀 ;对抗醋酸引起的血管通透性增加 ;对抗蛋清致大鼠足肿胀和棉球所致大鼠肉芽组织增生 ,与对照组比较有显著性差异。结论 :消炎利胆胶囊有明显地利胆抗炎作用。
Objective:TO investigate the anti inflammatory and cholagogic effect of Xiaoyanlidan capsule through animal experiment.Methods:Xiaoyanlidan capsules were used at dosage of 3,6 and 12 g/kg in order to observe the volume of the biliation,the swelling of the ears of mice caused by dimethy lbenzene,the permeability of the blood vessel by acetic acid,the swelling of feet of rats by egg white and the granuloma of rats by cotton ball method.Results:The cholagogic effect of Xiaoyanlidan maintained as long as 4 hours with the swelling of the ears of mice,the permeability of the blood vessel by acetic acid,the swelling of feet of rats by egg white and the granuloma in rats by the cotton ball being inhibited.Conclusion:Xiaoyanlidan capsule; anti inflammatory effect cholagogic effect.
关键词
消炎利胆胶囊
抗炎作用
利胆作用
中药
Xiaoyanlidan capsule
anti inflammatory effect
cholagogic effect
