人工流产围术期抗菌药物用药分析

Analysis of prophylactic application of antibiotics in artificial abortion perioperation

目的提高人工流产围术期抗菌药物预防使用的合理性。方法对医院门诊2010年3月和2011年3月人工流产手术患者300例进行用药调查,比较其围术期预防性使用抗菌药物情况。结果 2011年3月较2010年3月术前预防用药率、术中预防用药率明显升高,但术后预防用药率明显下降(P<0.05)。联合用药种类逐渐减少,单—用药逐渐增加;基本趋向于口服给药;但预防性用药种类趋向广谱抗菌药物,头孢菌素类药物比例增高。结论应更进一步严格掌握各类手术预防用药的指征;加强围术期预防性应用抗生素的管理;选择适当抗菌药物行围术期预防;定期对手术患者用药进行监测。

Objective To improve the rationality of the prophylactic application of antibiotics in artificial abortion perioperation.Methods Indagated 300 cases of abortion drug investigation,compared the perioperative prophylactic use of antimicrobial drug.Results March 2011 compared with March 2010,the rate of preoperative prophylaxis,intraoperative prophylaxis was significantly increased,but decreased rate of postoperative prophylaxis（P〈0.05）.Types of combination therapy decreased,single-medication and gradually increased;Basic tended to oral administration;Type of preventive medication,but tend to broad-spectrum antibiotics,increased the proportion of cephalosporins.Conclusion Various types of surgery should be strictly controlled to prevent further drug indications;Enhance perioperative prophylactic antibiotic administration;Select the appropriate line of perioperative antibiotic prophylaxis;Regular monitoring of patients undergoing treatment.