重症患者早期肠内营养支持治疗的临床研究

Clinical Study on the Effect of Early Enteral Nutrition in Critically Ill Patients

目的探讨重症患者早期肠内营养支持治疗效果。方法 100例重症患者按给养方式分为肠外营养组40例(PN)和肠内营养组60例(EEN),入ICU 48h内分别进行肠外营养和肠内营养,EEN组分为达标组35例(A组)和未达标组25例(B组)。结果治疗后EEN组和PN组血浆中TP、Alb、Hb均显著升高(P<0.05),EEN组与PN组及A组与B组间有显著差异(P<0.05)。PN组ALT、Cr较EEN组显著升高,EEN组CRP下降较PN组显著(P<0.05)。A组与B组ALT、Cr、CRP比较有显著差异(P<0.05)。结论早期达标的肠内营养能显著改善患者营养状况,保护消化道黏膜防止并发症的发生。

Objective To investigate the effect of early enteral nutrition（EEN） in critically ill patients. Methods All 100 cases of critically ill patients were divided into parenteral nutrition（PN） group of 40 cases and EEN group of 60 cases,they were given r^pectively PN and EEN within 48h when in the ICU. EEN group was divided into the up to scratch group of 3＇5 cases（group A）and not-up to scratch group of 25cases（group B）. Results After treatment,TP,Alb and Hb of PN and EEN group significantly increased（P〈0.01）, and there were significant differences of them between PN and EEN group as well as A and B group （P〈0.05）. The ALT and Cr of PN increased higher than EEN group（P〈0.05）,and the CRP of EEN group decreased lower than PN group（P〈0.05）.There were sig- nificant differences of ALT,CrA and CRP between A and B group （P〈0.05）. Conclusion The EEN up to scratch can significantly improve the nutritional status of critically ill patients, protect the gastrointestinal mucosa, prevent complications.