非酒精中毒性韦尼克脑病的MRI诊断价值

Diagnostic Value of MRI for Non-alcoholic Wernicke's Encephalopathy

目的评价颅脑MRI检查在非酒精中毒性韦尼克脑病诊断中的价值。方法对4例非酒精中毒性韦尼克脑病患者的临床特征、颅脑MRI影像及治疗转归等资料进行统计、对比、分析。结果本组颅脑MRI显示,两侧丘脑内侧、第三脑室周围、导水管周围、前联合、视交叉、延髓背侧可见多发对称性长T1长T2信号影,T2FLAIR呈高信号影,两侧侧脑室旁T2FLAIR可见多发小片状高信号影,脑室系统未见异常,中线结果居中。随访显示4例康复患者,随着临床表现好转,其颅脑MRI异常信号逐渐消失。结论颅脑MRI检查对非酒精中毒性韦尼克脑病具有重要诊断价值,其异常信号显示的范围反映了疾病的严重程度。

Objective To evaluate the diagnostic value of cranial MRI for non-alcoholic Wernicke＇s encephalopathy. Methods Clinical features,cranial MRI images and treatment outcome and other data of four cases of non-alcoholic Wernicke＇s encephalopathy patients were compared and statistically analyzed. Results The cranial MRI showed that both sides of the medial hypothalamus, three ventricle around inside the thalamus,periaqueduct,the former joint, optic chiasm, dorsal medulla had multiple symmetric long T1,T2 signal intensity,T2FLAIR showed high signal intensity,and both sides lateral side T2FLAIR seen multiple small pieces of high signal intensity,ventricular system was normal,and the results of the center line was central. Follow-up showed four cases of patients of rehabilitation with clinical improvement,their cranial MRI signal abnormalities gradually disappeared. Conclusion Cranial MRI examination for non-alcoholic Wernicke＇s encephalopathy has important diagnostic value,and the range of the abnormal signal display reflects the severity of the disease.