乳腺癌根治术后锁骨上淋巴结转移及远处转移病例临床分析

The Clinical Analysis of Supraclavicular Lymph Nodes and Distant Metastases after Radical Mastectomy

目的 探讨乳腺瘤根治术后锁骨上淋巴结转移及远处转移病例的临床病程及预后。方法 共收治109例,其中锁骨上淋巴结转移26例(A组);远处转移83例(B组)。总结两组病例初次治疗后出现转移的时间(简称为转移时间)及生存率等情况。结果 A、B两组病例的转移时间(中位数)为16及21个月,P>0.05。A组54%在135个月(2～34个月)内出现远处转移;B组37%在6个月(0～80个月)内出现其他部位的远处转移,P>0.05。两组病例的2年和5年生存率分别为442%、109%(A组)及431%、136%(B组),P>0.05。结论 本文提示乳腺癌术后锁骨上淋巴结转移病例的临床病程及生存率与远处转移病例的相近。

Objective To analyse the clinical course and prognosis of patients with supraclavicular lymph-node metastasis, and other distant metastasis following radical mastectomy. Methods 109 cases were reviewed, including 26 cases with supraclavicular lymph node metastases (group A) and 83 cases with distant metastases (group B). The time from initial treatment of primary tumor to metastases (time of metastases) and the survival rate of the two groups were investigated. Results The median time of metastases was 16 months (in group A) and 21 months (in group B), ( P >0.05).54% of cases in group A developed metastasis in the first 13.5 months (2～34 months), 37% of cases in group B developed distant metastasis in the first 6 months (0～80 months), ( P >0.05). The 2-, 5-year survival rates were 44.2%, 10.9% and 43.1%, 13.6% for in group A patients and B,respectively( P >0.05). Conclusions The results showed that patients with supraclavicular lymph nodes and distant metastases had similar clinical courses and survival rates.