益气养阴润肠汤改善结肠黑变病小鼠肠动力的实验观察

Experimental Observation on Supplementing Qi And Nourishing Yin Improving Enterokinesia of Mice With Colon Melanosis

目的:研究益气养阴润肠汤改善结肠黑变病小鼠肠动力效果,为临床提供实验依据。方法:将48只小鼠随机分为正常组,模型组,益气养阴剂高、中、低剂量组,福松组,观测各组碳末推进率。结果:益气养阴润肠汤(黄芪20 g,党参10 g,当归10g,陈皮10 g,升麻10 g,白术15 g,玄参10 g,麦冬10 g,生地黄10 g,肉桂2 g,甘草3 g)各剂量组的碳末推进率均明显提高,中、高剂量组优于对照组。结论:益气养阴润肠汤能促进肠动力,是治疗结肠黑变病的有效方法。

Objective：Study the effect of supplementing qi and nourishing yin improving enterokinesia of mice with colon melanosis.So that can provide the evidence for clinical practice.Methods：48 mice randomly divided into normal group,model group,supplementing qi and nourishing yin,high,medium and low dose group,Forlax group.Observe the carbon drive rates of each group.Results：Supplementing qi and nourishing yin decoction（astragalus 20 g,dangshen 10 g,angelica 10 g,chenpi10 g,cohosh 10 g,white atractylodes 15 g,igwort 10 g,creeping liriope 10 g,Rehmannia Root 10 g,cinnamon 2 g,licorice 3 g） Each dose group of carbon drive rates increases significantly.Medium and high dose group were better than the control group.Conclusion：Supplementing qi and nourishing yin decoction can promote bowel power.It is the effective method to treat the colon melanosis.