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CyclinB1、Ki-67在脑胶质瘤中的表达意义研究

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摘要 肿瘤增殖活性的检测对于判断肿瘤的恶性程度,预见其生物学活性,评估预后及选择适当的治疗措施很重要,Ki-67是一种与细胞增殖密切相关的核抗原,存在于细胞周期G1后期、S、G2、M期,是应用最广泛的增殖细胞标记之一。CyclinB1已有报道多种肿瘤都出现高表达,促进生长控制的缺失,
出处 《中国实验诊断学》 北大核心 2011年第12期2077-2079,共3页 Chinese Journal of Laboratory Diagnosis
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  • 1Wang W,Heideman L,Chung C S,et al.Cell2cycle arrest at G2PM andgrowth inhibition by apigenin in human colon carcinoma cell lines[J].MolCarcinog,2000,28(2):102.
  • 2Ho YS,Duh J S,Jeng J H,et al.Griseofulvin potentiates antitumorigene2sis effects of nocodazole through induction of apoptosis and G2PM cell cyclearrest in human colorectal cancer cells[J].Int J Cancer,2001,91(3):393.
  • 3Schulter C,Duchrow M,Wohlenberg C,et al.Molecular cloing of the cell proliferation associated nuclear antigen defined by antibody Ki67:an unique gene encoding for a new PEST protein[J].J Cell Biol,1993,123(3):513.
  • 4Namita S,peter A,Ki67:structure,function and new antibodies[J].J Pathol,1992,168:161.
  • 5Ozen O,Demirhan B,Aftinors N,Corrdation between histological grade and MIB-1 and P53 immunoreactivity in meningiomas[J].Clin Neuropathol,2005,24(5):219.
  • 6Jin Y H,Park ck,Expression of lyclin b1 and cdc2 in nodal non-Hodgkin's lymphoma and its prognostic implication[J].J med sci,2002,17(3):322.
  • 7Kawamoto H,Koizumi H,U chikoshi T,Expression of the G2-M checkpoint regulators cyclin b1 and cdc2 in nonmalignant and malignant huan breat lesions immunocy to chemical and quantitative image analyses[J].Am J pathol,1997,150(1).
  • 8Aunter T,Pines J.Cyclins and Cancer ⅡCyclin D and CDK in2hibitors come and age[J].Cell,1994,79 (4):5732.

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