热敏灸和针刺治疗乳腺增生病对比观察

Comparative Observations on Heat-sensitive Point Moxibustion and Acupuncture in the Treatment of Mammary Hyperplasia

目的观察热敏灸和针刺治疗乳腺增生病的临床疗效。方法将66例患者随机分为热敏灸组(34例)和针刺组(32例),两组均治疗3个月经周期后观察疗效及治疗前后血清雌二醇(E2)、泌乳素(PRL)、孕酮(P)的变化。半年后随访了解其复发率,采用《现代中医乳房病学》有关乳腺增生评分表为观察指标,对两组患者治疗前后分别测定肿块的质地、大小、范围、触痛、疼痛等进行计分以评价治疗效果。结果热敏灸组总有效率为88.2%,针刺组为65.6%,比较差异具有统计学意义(P<0.01);两组均能降低E2、PRL水平,治疗组优于针刺组(P<0.05),而对P水平的影响,两组均无统计学差异(P>0.05);热敏灸组复发率明显低于针刺组(P<0.01)。结论 热敏灸法治疗乳腺增生病的近期和远期疗效均优于针刺法。

Objective To investigate the clinical efficacies of heat-sensitive point moxibustion and acupuncture in treating mammary hyperplasia. Methods Sixty-six patients were randomly allocated to a heat-sensitive point moxibustion group （34 cases） and an acupuncture group （32 cases）. The therapeutic effects and post-treatment changes in serum estradiol （E2）, prolactin （PRL） and progesterone （P） were evaluated in both groups after treatment for three menstrual cycles. T A follow-up was carried out after six months to examine the recurrence rate. The lump consistency, size, extent, tenderness and pain were scored using the mammary hyperplasia score scale in The Modern Mastotic Studies of Traditional Chinese Medicine as the observation index in the two groups of patients before and after treatment to evaluate the therapeutic effects. Results The total efficacy rate was 88.2% in the heat-sensitive point moxibustion group and 65.6% in the acupuncture group. The difference was statistically significant （P〈0.01）. E2 and PRL levels fell in both groups after treatment and did more in the heat-sensitive point moxibustion group than in the acupuncture group （P〈0.05）. There was no statistically significant pre-treatment difference in P levels in both groups （P〉0.05）. The recurrence rate was significantly lower in the heat-sensitive point moxibustion group than in the acupuncture group （P〈0.01）. Conclusion Both the short-term and long-term effects of heat-sensitive point moxibustion were better than those of acupuncture in the treatment of mammary hyperplasia.